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Jung-Ae Kim Selected Research

1- (1- hydroxy- 6,6,9- trimethyl- 6a,7,8,9,10,10a- hexahydro- 6H- benzo(c)chromen- 2- yl)ethanone

1/2012Anti-tumor activity of the novel hexahydrocannabinol analog LYR-8 in Human colorectal tumor xenograft is mediated through the inhibition of Akt and hypoxia-inducible factor-1α activation.
1/2011Novel hexahydrocannabinol analogs as potential anti-cancer agents inhibit cell proliferation and tumor angiogenesis.
7/2010Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependent NSAID-activated gene-1 in colon cancer cells.

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Jung-Ae Kim Research Topics

Disease

51Neoplasms (Cancer)
09/2021 - 01/2002
27Inflammation (Inflammations)
01/2021 - 02/2006
20Breast Neoplasms (Breast Cancer)
12/2020 - 09/2008
19Colitis
01/2021 - 11/2008
14Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2021 - 06/2008
13Hypoxia (Hypoxemia)
12/2020 - 09/2008
10Hepatocellular Carcinoma (Hepatoma)
12/2022 - 12/2002
9Colonic Neoplasms (Colon Cancer)
10/2018 - 06/2006
6Body Weight (Weight, Body)
01/2021 - 10/2003
5Weight Loss (Weight Reduction)
01/2021 - 11/2008
5Lung Neoplasms (Lung Cancer)
01/2021 - 01/2015
5Neoplasm Metastasis (Metastasis)
01/2018 - 01/2011
5Neuroblastoma
01/2009 - 01/2002
4Triple Negative Breast Neoplasms
01/2018 - 11/2016
3Edema (Dropsy)
01/2021 - 02/2006
3Colorectal Neoplasms (Colorectal Cancer)
12/2020 - 02/2011
3Obesity
01/2020 - 10/2009
3Anaphylaxis (Anaphylactic Shock)
09/2019 - 01/2017
3Carcinoma (Carcinomatosis)
05/2012 - 05/2006
3Pathologic Neovascularization
02/2011 - 04/2009
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2021 - 01/2018
2Glioblastoma (Glioblastoma Multiforme)
01/2021 - 04/2008
2Necrosis
12/2020 - 11/2014
2Infections
01/2020 - 10/2006
2Hypertension (High Blood Pressure)
04/2017 - 11/2011

Drug/Important Bio-Agent (IBA)

16Pharmaceutical PreparationsIBA
12/2021 - 11/2004
14Reactive Oxygen Species (Oxygen Radicals)IBA
10/2018 - 12/2002
11Proteins (Proteins, Gene)FDA Link
06/2021 - 06/2007
11Peroxidase (Myeloperoxidase)IBA
01/2021 - 11/2008
11CytokinesIBA
01/2021 - 02/2008
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2017 - 09/2008
9Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2021 - 02/2008
7AntioxidantsIBA
01/2021 - 07/2004
7NADPH Oxidases (NAD(P)H oxidase)IBA
10/2018 - 04/2004
6Dextran SulfateIBA
01/2021 - 01/2017
6EnzymesIBA
01/2018 - 10/2003
6Small Interfering RNA (siRNA)IBA
11/2016 - 07/2010
5Transcription Factors (Transcription Factor)IBA
11/2020 - 09/2008
5TamoxifenFDA LinkGeneric
04/2019 - 08/2009
5Serotonin (5 Hydroxytryptamine)IBA
01/2017 - 04/2014
5Sulfonic AcidsIBA
04/2014 - 11/2008
5FlavonoidsIBA
03/2013 - 10/2008
5NF-kappa B (NF-kB)IBA
11/2009 - 06/2008
4Interleukin-6 (Interleukin 6)IBA
01/2021 - 03/2012
4AcidsIBA
08/2018 - 10/2016
4ChemokinesIBA
02/2014 - 06/2008
4Capsaicin (Zostrix)FDA Link
01/2005 - 01/2002
3serotonin 7 receptorIBA
10/2021 - 11/2016
3pyridineIBA
09/2021 - 01/2018
3Phosphotransferases (Kinase)IBA
09/2021 - 02/2012
32,4,5-trimethylpyridin-3-olIBA
01/2021 - 10/2018
3Biological ProductsIBA
09/2019 - 07/2015
3CateninsIBA
10/2018 - 01/2015
3Cisplatin (Platino)FDA LinkGeneric
10/2018 - 01/2015
3Sunitinib (Sutent)FDA Link
10/2018 - 06/2016
3matrigelIBA
01/2018 - 06/2015
3Matrix Metalloproteinases (MMPs)IBA
06/2015 - 07/2007
3Ethanol (Ethyl Alcohol)IBA
06/2014 - 10/2003
3Interleukin-8 (Interleukin 8)IBA
04/2014 - 11/2008
3Cyclooxygenase 2 (Cyclooxygenase-2)IBA
02/2014 - 01/2007
3Doxorubicin (Adriamycin)FDA LinkGeneric
03/2013 - 09/2008
3Transcription Factor AP-1 (Transcription Factor AP 1)IBA
10/2012 - 08/2009
31- (1- hydroxy- 6,6,9- trimethyl- 6a,7,8,9,10,10a- hexahydro- 6H- benzo(c)chromen- 2- yl)ethanoneIBA
01/2012 - 07/2010
3Clotrimazole (Lotrimin)FDA LinkGeneric
11/2008 - 09/2006
3asiatic acidIBA
01/2007 - 12/2002
3Poloxamer (Poloxamer 407)IBA
09/2006 - 08/2005
2GemcitabineFDA Link
10/2021 - 08/2015
2Mesalamine (Mesalazine)FDA LinkGeneric
01/2021 - 07/2014
2Sulfasalazine (Azulfidine)FDA LinkGeneric
01/2021 - 07/2014
2A-factor (Streptomyces)IBA
01/2021 - 05/2012
2BJ-1108IBA
01/2021 - 01/2016
2Biomarkers (Surrogate Marker)IBA
12/2020 - 10/2016
2Histones (Histone)IBA
12/2020 - 07/2007
2Oxygen (Dioxygen)IBA
12/2020 - 01/2017
2Lysine (L-Lysine)FDA Link
12/2020 - 01/2017
2Cadherins (E-Cadherin)IBA
12/2020 - 01/2018
2tofacitinibIBA
10/2020 - 04/2020
2Estrogen ReceptorsIBA
04/2019 - 10/2012
2Anti-Allergic Agents (Antiallergic Agents)IBA
01/2018 - 01/2017
2Sirtuin 1IBA
01/2018 - 01/2017
2cathepsin SIBA
01/2018 - 01/2017
2Matrix Metalloproteinase 9 (Gelatinase B)IBA
01/2018 - 10/2008
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2018 - 10/2017
2LigandsIBA
10/2017 - 09/2009
2AMP-Activated Protein KinasesIBA
01/2017 - 06/2015
2Tryptophan HydroxylaseIBA
01/2017 - 11/2016
2Hormones (Hormone)IBA
01/2017 - 11/2016
2Serotonin ReceptorsIBA
01/2017 - 04/2014
2tyrosine receptor (receptor, tyrosine)IBA
06/2016 - 02/2012
2Antineoplastic Agents (Antineoplastics)IBA
06/2016 - 01/2016
2Pyruvate KinaseIBA
08/2015 - 04/2015
27-O-succinyl macrolactin AIBA
01/2015 - 07/2014
2Fluorouracil (Carac)FDA LinkGeneric
01/2015 - 05/2006
2InterleukinsIBA
11/2014 - 01/2009
2Peptides (Polypeptides)IBA
05/2013 - 07/2004
2xanthohumolIBA
03/2013 - 01/2012

Therapy/Procedure

12Therapeutics
01/2021 - 05/2005
8Oral Administration
01/2021 - 10/2003
4Drug Therapy (Chemotherapy)
11/2016 - 11/2004
2Glycemic Control
01/2020 - 04/2017